YouTube Channel

Adapting my teaching materials for the COVID-19 global pandemic encouraged me to create a YouTube channel… here is what resulted! So far, it contains videos from the graduate TMS course I’ve co-taught twice now at UF, as well as videos related to outreach.

Kathleen Hupfeld

Videos related to grad school & neuroscience – brain stimulation, neuroimaging, etc.

Kathleen Hupfeld
I created this talk for NASA's Human Research Program (HRP) annual Investigators' Workshop (IWS) in 2021. The meeting was hosted virtually due to COVID-19, so I pre-recorded my talk and then engaged in Q&A with other human spaceflight researchers during a synchronous session.
This video shows the brain both pre- and post-flight for one astronaut who completed a multi-month mission to the International Space Station. Here we highlight pre- to post-flight compression of the gray matter at the top of the brain. To read more on these findings, please see our paper: Hupfeld, K. E., McGregor, H. R., Lee, J. K., Beltran, N. E., Kofman, I. S., De Dios, Y. E., ... & Alzheimer’s Disease Neuroimaging Initiative. (2020). The Impact of 6 and 12 Months in Space on Human Brain Structure and Intracranial Fluid Shifts. Cerebral cortex communications, 1(1), tgaa023. https://academic.oup.com/cercorcomms/article/1/1/tgaa023/5857115?login=true
This video shows the brain both pre- and post-flight for one astronaut who completed a multi-month mission to the International Space Station. Here we highlight pre- to post-flight expansion of the lateral ventricles. To read more on these findings, please see our paper: Hupfeld, K. E., McGregor, H. R., Lee, J. K., Beltran, N. E., Kofman, I. S., De Dios, Y. E., ... & Alzheimer’s Disease Neuroimaging Initiative. (2020). The Impact of 6 and 12 Months in Space on Human Brain Structure and Intracranial Fluid Shifts. Cerebral cortex communications, 1(1), tgaa023. https://academic.oup.com/cercorcomms/article/1/1/tgaa023/5857115?login=true
I created this video for the 2021 Florida Regional Junior Science, Engineering, and Humanities Symposium (JSEHS), which is an awesome multi-day event geared at engaging high school students in the scientific process, allowing them to present talks and posters on their own research and engage with researchers at local institutions, like the University of Florida. In the video, I tell about my unfolding STEM story -- from my work as an undergrad student researcher at Elon University to my current position in the final year of my PhD at the University of Florida. I hope you enjoy it! For more information about the FL Regional JSEHS, see their site here: https://www.cpet.ufl.edu/students/junior-science-engineering--humanities-symposium/
In this video, we show a brief overview of an experiment aiming to test the effect of motor task (i.e., index finger abduction, pincer grip, and power grip) on cortical silent period (cSP) duration. This experiment was adapted from a previous study by Tinnazi and colleagues in 2006: Säisänen, L., Pirinen, E., Teitti, S., Könönen, M., Julkunen, P., Määttä, S., & Karhu, J. (2008). Factors influencing cortical silent period: optimized stimulus location, intensity and muscle contraction. Journal of neuroscience methods, 169(1), 231-238. In the video, we also refer to our recent paper, Hupfeld et al. 2020 in the Journal of Neuroscience Methods, which discusses methodological considerations for designing cSP experiments and the effects of different post-processing choices: Hupfeld, K. E., Ketcham, C. J., & Schneider, H. D. (2017). Transcranial direct current stimulation (tDCS) to Broca’s area: persisting effects on non-verbal motor behaviors. Neurological Disorders and Therapeutics, 1(1), 1-5.
In this video, we show a brief overview of an experiment aiming to test the effect of motor task (i.e., index finger abduction, pincer grip, and power grip) on cortical silent period (cSP) duration. This experiment was adapted from a previous study by Tinnazi and colleagues in 2006: Tinazzi, M., Farina, S., Tamburin, S., Facchini, S., Fiaschi, A., Restivo, D., & Berardelli, A. (2003). Task-dependent modulation of excitatory and inhibitory functions within the human primary motor cortex. Experimental brain research, 150(2), 222-229. In the video, we also refer to our recent paper, Hupfeld et al. 2020 in the Journal of Neuroscience Methods, which discusses methodological considerations for designing cSP experiments and the effects of different post-processing choices: Hupfeld, K. E., Ketcham, C. J., & Schneider, H. D. (2017). Transcranial direct current stimulation (tDCS) to Broca’s area: persisting effects on non-verbal motor behaviors. Neurological Disorders and Therapeutics, 1(1), 1-5.
We briefly review the experimental set-up for using transcranial magnetic stimulation (TMS) to elicit cortical silent period (cSPs). For further reading on methodological considerations for cSP studies, please see our recent review paper: Hupfeld, K. E., Swanson, C. W., Fling, B. W., & Seidler, R. D. (2020). TMS-induced silent periods: A review of methods and call for consistency. Journal of Neuroscience Methods, 108950 https://www.sciencedirect.com/science/article/abs/pii/S0165027020303733
We discuss in detail the steps required to set up a TMS experiment, with a focus on the motor system and collecting cortical silent periods (cSPs)
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